The goal of this clinical trial was to evaluate whether a low-FODMAP diet and probiotic supplements could reduce gastrointestinal (GI) symptoms and behavior problems in children with autism spectrum disorder (ASD) who also experienced GI issues. The main questions it aimed to answer were: Did a low-FODMAP diet and/or probiotics improve GI symptoms such as constipation, diarrhea, and abdominal pain? Did these interventions help reduce behavior problems such as irritability, lethargy, stereotypy, hyperactivity, and speech disorder ? Researchers compared two groups: 1. Children who received a daily probiotic supplement containing 4 strains for 4 weeks 2. Children who received both the probiotic supplement and followed a low-FODMAP diet This comparison aimed to determine whether the combination of diet and probiotics had greater benefits than probiotics alone. Participants: Took the assigned intervention(s) for 4 weeks Provided stool samples for gut microbiota analysis Completed assessments of GI symptoms and behavior using validated questionnaires
Age range
6 Years – 12 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change in Aberrant Behavior Checklist (ABC) Irritability Subscale Score
Timeframe: Baseline and after 4 weeks of intervention
Change in Aberrant Behavior Checklist (ABC) Hyperactivity Subscale Score
Timeframe: Baseline and after 4 weeks of intervention
Change in Aberrant Behavior Checklist (ABC) Lethargy-Social Withdrawal Subscale Score
Timeframe: Baseline and after 4 weeks of intervention
Change in Aberrant Behavior Checklist (ABC) Stereotypy Subscale Score
Timeframe: Baseline and after 4 weeks of intervention
Change in Aberrant Behavior Checklist (ABC) Inappropriate Speech Subscale Score
Timeframe: Baseline and after 4 weeks of intervention
Change in Presence of Functional Gastrointestinal Symptoms as Measured by the QPGS-RIII
Timeframe: Baseline and after 4 weeks of intervention