This is a single-center, non-randomized, open-label, single-dose, Phase I clinical study to evaluate the mass balance and biotransformation, safety and tolerability of WPV01 in healthy adult chinese male participants following a single oral administration of \[14C\] WPV01.
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Total recovery and cumulative recovery of total WPV01-related radioactive material in excreta (urine and feces)
Timeframe: Up to 168 hours(approx) from drug administration
Total radioactivity of WPV01-related substances in human plasma
Timeframe: Up to 168 hours(approx) from drug administration
Ratio of total WPV01-related radioactivity concentrations in human whole blood and plasma at different time points
Timeframe: Up to 168 hours(approx) from drug administration
WPV01 and its metabolites in human plasma as a percentage of total plasma radioactivity exposure
Timeframe: Up to 168 hours(approx) from drug administration
WPV01 and its metabolites in human excreta (urine and feces) as a percentage of total urine/feces radioactivity exposure
Timeframe: Up to 168 hours(approx) from drug administration
Identification of metabolites in plasma
Timeframe: Up to 168 hours(approx) from drug administration
Identification of metabolites in urine
Timeframe: Up to 168 hours(approx) from drug administration
Identification of metabolites in feces
Timeframe: Up to 168 hours(approx) from drug administration