A Temporal Variability Study of Remimazolam for General Anesthesia Induction and Maintenance (NCT07079800) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
A Temporal Variability Study of Remimazolam for General Anesthesia Induction and Maintenance
China188 participantsStarted 2025-06-17
Plain-language summary
The purpose of this study was to observe and compare the differences in plasma concentration, dosage and carboxylesterase 1 activity of remimazolam when remimazolam is used for general anesthesia induction and maintenance at different times of the day, and to explore the effect of time rhythm on the pharmacokinetics and pharmacodynamics of remimazolam, so as to provide new ideas and clinical basis for optimizing medication regimens and anesthesia management.
Who can participate
Age range18 Years – 75 Years
SexALL
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Inclusion criteria
✓. Age 18-65 years old, ASAI-II class, BMI18.5-25kg/m\^2;