By InvitationNot Applicable

Dyed vs. Undyed Polyglactin Sutures in Cutaneous Surgery

United States50 participantsStarted 2025-08

Plain-language summary

Purpose - This exploratory, split-wound study aims to evaluate the potential difference in skin reactions to two different types of sutures, dyed and undyed, used to close wounds after surgery. The study will assess whether dyed sutures to elicit increased tissue reactivity like redness, itching, and scarring and whether undyed sutures may be more optimal for wound healing and cosmetic response. Enrollment into the study and data collection is expected to take approximately 3-6 months. Follow-up visits will be chosen at 2 weeks, 4 weeks, and 3 months post-surgery, which is standard practice for monitoring healing and checking for complications such as infection or abnormal scarring. Primary Objective - The primary objective is to assess the response of wounds closed with both dyed and undyed sutures after cutaneous surgery to determine if there is a difference in wound healing and tissue reactivity with one compared to the other. Enrollment into the study and data collection is expected to take approximately 3-6 months. Follow-up visits will be chosen at 2 weeks, 4 weeks, and 3 months post-surgery, which is standard practice for monitoring healing and checking for complications such as infection or abnormal scarring.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients who are scheduled for a standard of care surgical excision Exclusion Criteria: * Patients who are unable to give informed consent

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Clinical Erythema Assessment scale

Timeframe: 2 weeks post-procedure

Clinical Erythema Assessment scale

Timeframe: 4 weeks post-procedure

Clinical Erythema Assessment scale

Timeframe: 3 months post-procedure

Presence of Hypertrophic Scarring

Timeframe: 2 weeks post-procedure

Presence of Hypertrophic Scarring

Timeframe: 4 weeks post-procedure

Presence of Hypertrophic Scarring

Timeframe: 3 months post-procedure

Presence of Suture Extrusion

Timeframe: 2 weeks post-procedure

Presence of Suture Extrusion

Trial details

NCT IDNCT07078669

SponsorWest Virginia University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01

View on ClinicalTrials.gov More Wound Closure trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients who are scheduled for a standard of care surgical excision Exclusion Criteria: * Patients who are unable to give informed consent

What they're measuring

Clinical Erythema Assessment scale

Timeframe: 2 weeks post-procedure

Clinical Erythema Assessment scale

Timeframe: 4 weeks post-procedure

Clinical Erythema Assessment scale

Timeframe: 3 months post-procedure

Presence of Hypertrophic Scarring

Timeframe: 2 weeks post-procedure

Presence of Hypertrophic Scarring

Timeframe: 4 weeks post-procedure

Presence of Hypertrophic Scarring

Timeframe: 3 months post-procedure

Presence of Suture Extrusion

Timeframe: 2 weeks post-procedure

Presence of Suture Extrusion