CompletedNot Applicable

In Vitro and in Vivo Evaluation of the Anti-Inflammatory and Antithrombotic Synergy of Vitamin C and Bioflavonoids in Healthy Subjects

Greece20 participantsStarted 2024-10-01

Plain-language summary

This study aimed to evaluate the antioxidant potential, and especially the anti-inflammatory and antiplatelet biological efficacy and synergy of a high dose (1 g) vitamin C - low dose (50 mg) bioflavonoid (VCF) based supplement using both in vitro approaches and an and in vivo clinical trial in human platelets from healthy subjects administered orally for 1 month the VCF supplement (VCF Group) versus the administration of a 1 g vitamin C supplement (VC Group).

Who can participate

Age range18 Years – 60 Years

SexALL

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Inclusion Criteria: Subjects should: * not have a pathological condition related to platelet and leukocyte activity * not have a chronic pathological condition * have a normal BMI * not take medications that have anti-inflammatory and/or antithrombotic effects Exclusion Criteria: If Subjects * have a pathological condition related to platelet and leukocyte activity * have a chronic pathological condition * not have a normal BMI * take medications that have anti-inflammatory and/or antithrombotic effects

What they're measuring

Anti-platelet cardio-protective efficacy

Timeframe: 1 month

Trial details

NCT IDNCT07061431

SponsorDemocritus University of Thrace

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-03-31

View on ClinicalTrials.gov More Cardio-protection trials