Stopped: Funding not received.
This study will investigate whether knee joint manipulation can improve neurocognitive and neuromuscular performance in individuals with a history of anterior cruciate ligament reconstruction (ACLR). Recruitment will consist of 30 participants aged 18-35 who are 4 months to 5 years post-ACLR and demonstrate measurable reaction time delays. Using a within-subject pre-post design, participants will complete a battery of neurocognitive and neuromuscular assessments, including visuomotor reaction time and dual-task hop testing, before and after knee joint manipulation(s). The main questions the investigators aim to address are: Aim 1: Evaluate the feasibility, acceptability, and applicability of integrating knee joint manipulation into post-ACLR rehabilitation using the Implementation and Outcomes Framework. Aim 2: Determine preliminary efficacy of knee joint manipulation on neurocognitive performance in individuals with ACLR.
Age range
18 Years – 35 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change in Simple Reaction Time
Timeframe: Baseline and up to 90 minutes after completion of joint manipulation (intervention)
Change in Lower Extremity Visuomotor Reaction Time
Timeframe: Baseline and up to 90 minutes after completion of joint manipulation (intervention)
Mean Feasibility of Joint Manipulation Score
Timeframe: Baseline and up to 90 minutes after completion of joint manipulation (intervention)
Mean Acceptability of Joint Manipulation Score
Timeframe: Baseline and up to 90 minutes after completion of joint manipulation (intervention)
Mean Appropriateness of Joint Manipulation Score
Timeframe: Baseline and up to 90 minutes after completion of joint manipulation (intervention)