RecruitingNot Applicable

Tumor-Lymph Node Mapping

United States10 participantsStarted 2026-04-13

Plain-language summary

The purpose of this study is to assess the feasibility and safety of ICG-guided intraoperative lymphography for detecting sentinel lymph nodes (SLN) in pediatric patients with solid tumors who require retroperitoneal lymph node dissection/sampling. This trial is a single-site cross-sectional study. The injection of ICG directly into lymphatics draining the primary tumor will take place at the time of operation after the patient is under anesthesia.

Who can participate

Age range1 Month – 17 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Any pediatric patient (under the age of 18 years) being treated at the University of Rochester Medical Center, Department of Surgery. * Diagnosed with pediatric solid tumor * Scheduled to undergo lymph node sampling as part of their clinical management. Exclusion Criteria: * Subjects with a history of iodide allergies. * Inability or unwillingness of research participant or parent/legal guardian to give written informed consent. * Currently pregnant. * Infants under 650 grams. * Patients with extensive prior surgery at the primary site or nodal basin expected to affect the lymphatic drainage.

What they're measuring

Percentage of Patients with Successful Sentinel Lymph Node (SLN) Detection Using ICG Fluorescence

Timeframe: Baseline

Trial details

NCT IDNCT07054944

SponsorUniversity of Rochester

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-07-30

Contact for this trial

Abdelhafeez Abdelhafeez, MD

Abdelhafeez_Abdelhafeez@URMC.Rochester.edu

View on ClinicalTrials.gov More Pediatric Solid Tumors trials