CompletedNot Applicable

Changes in Bruxism Activity After Periodontal Treatment in Patients With Periodontitis

Italy40 participantsStarted 2025-06-27

Plain-language summary

This controlled pre-post study evaluates the effect of non-surgical periodontal therapy on awake and sleep bruxism in patients with Stage III and IV periodontitis. Bruxism activity and periodontal status will be assessed at baseline and three months after treatment.

Who can participate

Age range

25 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age between 25 and 50 years * Good general health (ASA I or II) * Signed informed consent * Willingness to attend all study visits and follow instructions * For periodontitis group: diagnosis of Stage III or IV periodontitis according to the 2017 classification * For healthy control group: no clinical signs of periodontitis Exclusion Criteria: * Systemic diseases or medications affecting the periodontium (e.g., diabetes, immunosuppressants) * Antibiotic or anti-inflammatory therapy within the last 3 months * Periodontal treatment in the last 6 months * Smoking more than 10 cigarettes/day * Use of occlusal splints or bruxism-targeted therapy in the past 6 months * Pregnancy or lactation * Any condition impairing the ability to cooperate or comply with the study protocol

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Bruxism Episodes

Timeframe: Baseline and 3 months

Trial details

NCT IDNCT07053878

SponsorUniversity of Siena

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-10-30

View on ClinicalTrials.gov More Periodontitis trials

Who can participate

Age range

25 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.