The purpose of this study is to learn what happens to bomedemstat (MK-3543) in a person's body over time. Researchers will compare what happens to bomedemstat in the body when it is given to participants with mild or moderate hepatic (liver) impairment and healthy participants. Participants will be allocated to one of three groups: mild hepatic impairment (HI), moderate HI, or healthy matched control. All participants will receive a single oral dose of bomedemstat on Day 1. Healthy control participants will be enrolled after hepatic impairment participants have been dosed. Healthy control participants will be matched for the mean age and mean body-mass index (BMI) of all participants with HI (mild and moderate HI combined) and sex to each HI group separately.
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Area Under the Concentration-Time Curve from Time 0 to Infinity (AUC0-Inf) of Bomedemstat in Participants with Mild Hepatic Impairment (HI)
Timeframe: Up to 216 hours
Maximum Plasma Concentration (Cmax) of Bomedemstat in Participants with Mild HI
Timeframe: Up to 216 hours
AUC0-Inf of Bomedemstat in Participants with Moderate HI
Timeframe: Up to 216 hours
Cmax of Bomedemstat in Participants with Moderate HI
Timeframe: Up to 216 hours