CompletedNot Applicable

Effectiveness of E-prf Alone and in Combination With Bioactive Glass Nanoparticles in Grade II Furcation Defects

Egypt30 participantsStarted 2024-01-03

Plain-language summary

The aim of the study is to evaluate and compare the effectiveness of extended platelet-rich fibrin (ePRF) alone and in combination with bioactive glass nanoparticles in the treatment of grade II furcation defects clinically and radiographically.

Who can participate

Age range18 Years – 50 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Presence of Glickman's grade II furcation defects in molars probing depth (PD) ≥5 mm horizontal PD ≥3 mm. * The patients are in good systemic health and had not undergone any periodontal surgery in the areas to be treated within the prior 12 months. Exclusion Criteria: * Smokers and tobacco chewers. * Patients that take any medications within the past 6 months that could alter their periodontal status. * pregnant or lactating females. * Patients with known allergy to materials or drugs that will be used or prescribed in this study.

What they're measuring

The primary outcome will be the amount of bone fill vertically and horizontally obtained in the treatment of grade II furcation defects calculated from CBCT data in millimeters

Timeframe: 6 months follow up

Trial details

NCT IDNCT07042204

SponsorMerna Nasser Mohamed Mostafa Ibrahim Elnahas

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-03

View on ClinicalTrials.gov More Furcation Defects trials