The Phase 3 clinical trial of freeze-dried human rabies vaccine (human diploid cells) adopted a randomized, blinded, parallel control,non-inferiority design,and administered vaccines to participants aged 10 to 60 years with different immunization schedules (5-dose schedule group, two simple 4-dose schedule groups, and 2-1-1 schedule group) to evaluate the immunogenicity and safety of the vaccine.
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Antibody SCR for the 5-dose schedule group of the trial vaccine and the 5-dose schedule group of the control vaccine
Timeframe: 14 days after the first dose
Antibody GMC for the 5-dose schedule group of the trial vaccine and the 5-dose schedule group of the control vaccine
Timeframe: 14 days after the first dose
Antibody SCR for the simple 4-dose schedule group 1 of the trial vaccine and the 5-dose schedule group of the control vaccine
Timeframe: 14 days after the first dose
Antibody GMC for the simple 4-dose schedule group 1 of the trial vaccine and the 5-dose schedule of the control vaccine
Timeframe: 14 days after the first dose
Antibody SCR for the simple 4-dose schedule group 2 of the trial vaccine and the 5-dose schedule group of the control vaccine
Timeframe: 14 days after the first dose
Antibody GMC for the simple 4-dose schedule group 2 of the trial vaccine and the 5-dose schedule group of the control vaccine
Timeframe: 14 days after the first dose
Antibody SCR for the 2-1-1 schedule group of the trial vaccine and the 5-dose schedule group of the control vaccine
Timeframe: 14 days after the first dose
Antibody GMC for the 2-1-1 schedule group of the trial vaccine and the 5-dose schedule group of the control vaccine
Timeframe: 14 days after the first dose
Antibody SCR for the 5-dose schedule group of the trial vaccine and the 5-dose schedule group of the control vaccine
Timeframe: 14 days after full vaccination
Antibody SCR for the simple 4-dose schedule group 1 of the trial vaccine and the 5-dose schedule group of the control vaccine
Timeframe: 14 days after full vaccination
Antibody SCR for the simple 4-dose schedule group 2 of the trial vaccine and the 5-dose schedule group of the control vaccine
Timeframe: 14 days after full vaccination
Antibody SCR for the 2-1-1 schedule group of the trial vaccine and the 5-dose schedule group of the control vaccine
Timeframe: 14 days after full vaccination