Not Yet RecruitingNot Applicable

Exploring Substance Use, Sleep Disturbances and Reward Sensitivity

154 participantsStarted 2025-06-16

Plain-language summary

According to foreign medical studies, substance use is closely related to reward sensitivity and sleep patterns. The purpose of this research is to understand the relationship between these three factors, which will help improve medical treatment and overall care for substance misuse in the future. Participants will be randomized into CBTi and sleep education groups, and their substance/ alcohol use, sleep parameters and reward sensitivity will be measured at multiple time points.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Individuals who receive treatment services at Substance Abuse Assessment Clinic and other psychiatric out-patient clinics of Kwai Chung Hospital;
✓. Individuals who have problematic substance or alcohol use in the past 3 months, confirmed by scores higher than or equal to 1 in both part 1 and part 2 of Tobacco, Alcohol, Prescription medication, and other Substance use (TAPS);
✓. Individuals who have sleep disturbances, confirmed by a score higher than or equal to 8 on the Insomnia Severity Index (ISI).

Exclusion criteria

✕. Individuals who cannot understand Cantonese, or cannot read Traditional Chinese
✕. Individuals who cannot provide informed consent due to, for example, intoxication or abnormal mental state
✕. Individuals who report abnormal or unstable mental states, such as active psychotic symptoms or acute intoxication, at any point of the study
✕. Individuals who work overnight or have rotating shifts
✕. Individuals who report pregnancy or medical conditions (including sleep apnea) that may have a severe impact on sleep
✕. Individuals who use hypnotics regularly

What they're measuring

Insomnia Severity Index

Timeframe: From enrollment to the end of treatment at 8 weeks

Pittsburgh Sleep Quality Index

Timeframe: From enrollment to the end of treatment at 8 weeks

Drug Use Disorders Identification Test

Timeframe: From enrollment to the end of treatment at 8 weeks

Alcohol Use Disorders Identification Test

Timeframe: From enrollment to the end of treatment at 8 weeks

Trial details

NCT IDNCT07028346

SponsorKwai Chung Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-30

Contact for this trial

Mr. Lam

852-2959-8539 fritzyeung@ha.org.hk

View on ClinicalTrials.gov More Substance Abuse trials

Plain-language summary

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Individuals who receive treatment services at Substance Abuse Assessment Clinic and other psychiatric out-patient clinics of Kwai Chung Hospital;
✓. Individuals who have problematic substance or alcohol use in the past 3 months, confirmed by scores higher than or equal to 1 in both part 1 and part 2 of Tobacco, Alcohol, Prescription medication, and other Substance use (TAPS);
✓. Individuals who have sleep disturbances, confirmed by a score higher than or equal to 8 on the Insomnia Severity Index (ISI).

Exclusion criteria

✕. Individuals who cannot understand Cantonese, or cannot read Traditional Chinese
✕. Individuals who cannot provide informed consent due to, for example, intoxication or abnormal mental state
✕. Individuals who report abnormal or unstable mental states, such as active psychotic symptoms or acute intoxication, at any point of the study
✕. Individuals who work overnight or have rotating shifts
✕. Individuals who report pregnancy or medical conditions (including sleep apnea) that may have a severe impact on sleep
✕. Individuals who use hypnotics regularly

What they're measuring

Insomnia Severity Index

Timeframe: From enrollment to the end of treatment at 8 weeks

Pittsburgh Sleep Quality Index

Timeframe: From enrollment to the end of treatment at 8 weeks

Drug Use Disorders Identification Test

Timeframe: From enrollment to the end of treatment at 8 weeks

Alcohol Use Disorders Identification Test

Timeframe: From enrollment to the end of treatment at 8 weeks