Treatment With 5-AminoLEvuliNic Acid Before Cardiac Surgery

Inclusion Criteria: * Scheduled for non-emergent cardiac surgery under CPB (including coronary artery bypass grafting, valve replacement, valve repair or a combination thereof) * Signed informed consent * Age ≥18 years * Able and willing to comply with all study requirements Exclusion Criteria: * Female participants who are of childbearing potential who are either unable or unwilling to use highly effective contraception, or who are pregnant or breast feeding * History of hypersensitivity to 5-ALA, SFC and/or porphyrins * Acute or chronic types of porphyria * Known genetic haemochromatosis or clinically significant iron overload * History of clinically significant photosensitization * Current long-term (\> 3 months) use of amiodarone * Concomitant use of hypericin extract (including St John's Wort) or concomitant therapeutic dose oral iron replacement * Use of other investigational medical product(s) \< 28 days prior to study or 5 half-lives, whichever is longer * Cardiogenic shock/Low cardiac output syndrome requiring catecholamine infusion and/or mechanical circulatory support prior to induction of anaesthesia for cardiac surgery * Recent acute myocardial infarction * Cardiac surgery without cardiopulmonary bypass or induced fibrillating heart surgery * Inadequate renal or liver function * Any other condition which, in the opinion of the Investigator, makes the patient unsuitable for or may compromise their participation in the study