Predicting and Monitoring Spontaneous Bacterial Peritonitis in Cirrhotic Patients Using the Manso… (NCT07024355) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Predicting and Monitoring Spontaneous Bacterial Peritonitis in Cirrhotic Patients Using the Mansoura Scoring System
250 participantsStarted 2026-04-01
Plain-language summary
The aim of this prospective study was to examine predictors of SBP in order to develop a noninvasive method to identify or exclude an episode of SBP, for starting early treatment with antibiotics, so decrease morbidity and mortality in these patients.
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult patients aged \>18 years
* Diagnosed liver cirrhosis
* Presence of ascites
* Provided written informed consent
Exclusion Criteria:
* Use of antibiotics within the previous two weeks
* Prophylactic treatment for spontaneous bacterial peritonitis (SBP) prior to admission
* Ascites not related to portal hypertension, including:
* Peritoneal tuberculosis
* Peritoneal carcinomatosis
* Congestive heart failure
* Renal disease
* Pancreatitis
* Hemorrhagic ascites
* Secondary peritonitis
* Presence of infections other than SBP, including:
* Pneumonia
* Urinary tract infection
* Skin and soft tissue infection
* Presence of malignancy Hematologic diseases
* Use of antiplatelet drugs or non-steroidal anti-inflammatory drugs (NSAIDs)
* Receipt of platelet or blood transfusion prior to admission
* Diseases associated with elevated mean platelet volume (MPV), including:
* Diabetes mellitus
* Cardiovascular disease
* Hyperthyroidism
* Immune thrombocytopenia
* Myeloproliferative disorders
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Diagnostic Accuracy of the Mansoura Scoring System for Predicting Spontaneous Bacterial Peritonitis (SBP)
Timeframe: At hospital admission ( within 24 hours of admission)