Predicting and Monitoring Spontaneous Bacterial Peritonitis in Cirrhotic Patients Using the Manso… (NCT07024355) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Predicting and Monitoring Spontaneous Bacterial Peritonitis in Cirrhotic Patients Using the Mansoura Scoring System
250 participantsStarted 2026-04-01
Plain-language summary
The aim of this prospective study was to examine predictors of SBP in order to develop a noninvasive method to identify or exclude an episode of SBP, for starting early treatment with antibiotics, so decrease morbidity and mortality in these patients.
Who can participate
Age range18 Years – 60 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult patients aged \>18 years
* Diagnosed liver cirrhosis
* Presence of ascites
* Provided written informed consent
Exclusion Criteria:
* Use of antibiotics within the previous two weeks
* Prophylactic treatment for spontaneous bacterial peritonitis (SBP) prior to admission
* Ascites not related to portal hypertension, including:
* Peritoneal tuberculosis
* Peritoneal carcinomatosis
* Congestive heart failure
* Renal disease
* Pancreatitis
* Hemorrhagic ascites
* Secondary peritonitis
* Presence of infections other than SBP, including:
* Pneumonia
* Urinary tract infection
* Skin and soft tissue infection
* Presence of malignancy Hematologic diseases
* Use of antiplatelet drugs or non-steroidal anti-inflammatory drugs (NSAIDs)
* Receipt of platelet or blood transfusion prior to admission
* Diseases associated with elevated mean platelet volume (MPV), including:
* Diabetes mellitus
* Cardiovascular disease
* Hyperthyroidism
* Immune thrombocytopenia
* Myeloproliferative disorders
What they're measuring
1
Diagnostic Accuracy of the Mansoura Scoring System for Predicting Spontaneous Bacterial Peritonitis (SBP)
Timeframe: At hospital admission ( within 24 hours of admission)