CompletedNot Applicable

Predicting 28-Day Survival in OHCA Patients

Turkey (Türkiye)327 participantsStarted 2023-05-01

Plain-language summary

This prospective study aimed to identify clinical and laboratory predictors of return of spontaneous circulation (ROSC), 28-day survival, and favorable neurological outcomes in adult patients experiencing out-of-hospital cardiac arrest (OHCA) and brought to the emergency department (ED) by emergency medical services (EMS). Specifically, the prognostic value of hematologic, biochemical, and blood gas parameters on admission was assessed for ROSC, 28-day survival, and favorable neurological recovery. Additionally, the study investigated the influence of key patient-centered and prehospital variables, including demographic features, initial cardiac rhythm, and the timeliness and type of cardiopulmonary resuscitation (CPR), defibrillation, and airway interventions, on overall survival and neurological status.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: \- This study included 420 adult patients (aged ≥18 years) who were brought to our hospital's ED due to OHCA and who had initiated attempted resuscitation by EMS were initially screened for inclusion between May 2023 and May 2024. Exclusion Criteria: * Patients aged \< 18 years * Patients with in-hospital cardiac arrest * Patients who have suffered cardiac arrest due to major trauma, drowning, drug overdose, or known terminal illness * Patients with active hematologic malignancy * Patients with incomplete data regarding primary outcomes or admission laboratory tests

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Number of Participants with Return of Spontaneous Circulation (ROSC)

Timeframe: Assessed within the first 20 minutes after emergency department admission.

Number of Participants Alive at Day 28

Timeframe: Assessed within the first 20 minutes after emergency department admission.

Number of Participants with Favorable Neurological Outcome (CPC 1-2) at Day 28

Timeframe: Assessed within the first 20 minutes after emergency department admission.

Trial details

NCT IDNCT07023159

SponsorHaseki Training and Research Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-05-01

View on ClinicalTrials.gov More Out of Hospital Cardiac Arrest trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Number of Participants with Return of Spontaneous Circulation (ROSC)

Timeframe: Assessed within the first 20 minutes after emergency department admission.

Number of Participants Alive at Day 28

Timeframe: Assessed within the first 20 minutes after emergency department admission.

Number of Participants with Favorable Neurological Outcome (CPC 1-2) at Day 28

Timeframe: Assessed within the first 20 minutes after emergency department admission.