CompletedNot Applicable

Pectoral Nerve Block and Serratus Posterior Superior Intercostal Plane Block in Breast Cancer Surgery

Turkey (Türkiye)118 participantsStarted 2025-05-25

Plain-language summary

This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Pectoral Nerve Block (PECS II) and the Serratus Posterior Superior Intercostal Plane (SPSIP) Block in patients undergoing breast cancer surgery. The primary outcome is total opioid consumption in the first 24 hours. Secondary outcomes include pain scores (VAS), block performance time, number of needle passes, postoperative recovery quality (QoR-15), time to first analgesic request, and complications (hematoma, pneumothorax, local anesthetic toxicity, vascular puncture, infection).

Who can participate

Age range18 Years – 65 Years

SexFEMALE

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Inclusion Criteria: * Female patients aged 18-65 years * American Society of Anesthesiologists (ASA) physical status I-III * Body Mass Index (BMI) less than 35 kg/m² * Unilateral breast cancer surgery Exclusion Criteria: * Patient refusal to participate * BMI greater than or equal to 35 kg/m² * ASA physical status IV-V * Known allergy to any study medications * Pregnancy or breastfeeding * Presence of neuromuscular diseases * Chronic opioid use * Chronic pain syndromes * Significant organ failure (e.g., cardiac, hepatic, renal) * Contraindications to regional nerve blocks * Bilateral breast surgery

What they're measuring

Total opioid consumption

Timeframe: the first 24 hours postoperatively

Trial details

NCT IDNCT07001657

SponsorAntalya Training and Research Hospital

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2025-12-01

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