RecruitingPhase 2/3

Treatment Outcomes and Patient Satisfaction of Oral Lichen Planus Treatment

Saudi Arabia56 participantsStarted 2025-05-20

Plain-language summary

The goal of this clinical trial is to assess Honey in orabase (1:1) for treating patients with OLP and improving their quality of life: The research question aims to answer: Does honey in orabase (1:1) improve or reduce OLP symptoms compared to the standardized treatment by triamcinolone acetonide 0.1% drug and improve the patient's quality of life? Participants will: Take drug ABC or a placebo every day for 4 months Visit the clinic once every 2 weeks for checkups and tests Keep a diary of their symptoms and the number of times they use a rescue inhaler

Who can participate

Age range35 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with a clinical diagnosis of oral lichen planus * Symptomatic OLP lesions (erosive/atrophic) * Participants are between 35 and 60 years old, who are able to adhere to the study protocol, and sign informed consent. Exclusion Criteria: * Patients with other oral mucosal disorders, or systemic conditions influencing OLP or wound healing, allergies or hypersensitivity to honey or triamcinolone * Patients who administer systemic corticosteroids or immunosuppressive agents. * Pregnancy or lactation * Inability to comprehend or adhere to study directives * Patients who are not able to sign an informed written consent

What they're measuring

Clinical Assessment of OLP lesions using OLP score

Timeframe: baseline to 1 year

Pain assessment using Visual analogue scale (VAS)

Timeframe: baseline- to 1 year

Trial details

NCT IDNCT06988527

SponsorDar Al Uloom University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-15

Contact for this trial

Sally A ElHaddad, Assist Prof

00966011494 s.elhaddad@dau.edu.sa