4-day Plaque Accumulation Model Evaluating Compound Containing Gum

Inclusion Criteria: * Adult subjects between 18 and 65 years old * Willing to read and sign the IRB-approved informed consent. * Healthy, as determined by pertinent medical history at the study dentist's discretion. * A minimum of 20 natural teeth (excluding third molars) with at least two scorable surfaces per tooth (teeth with full crowns, large/extensive restorations on the interproximal areas, and orthodontic bands will not be included in the tooth count) * PLI of 2 or greater (Based on the Turesky modification of the Quigley and Hein Plaque Index) calculation based on a whole mouth plaque score. * Willing to comply with the study procedures. Exclusion Criteria: * Presence of any acute or chronic condition, organ system disease, or medication that, in the principal investigator's opinion, could compromise the subjects' ability to participate in the study. * Gross oral pathologies, including caries, calculus, or soft tissue conditions that show evidence of chronic neglect. * Evidence of acute periodontal conditions or periodontitis with pockets greater than 5 mm on more than one site * Use of antibiotics 30 days prior to or during the study * Requiring the need for antibiotic premedication prior to dental procedures * Sensitivity to bovine products (lactoferrin) or any of the listed inactive ingredients * Orthodontic appliances or any removable, except lingual bar retainers * Self-reported pregnant, wanting to get pregnant, or breast-feeding female, * Self-reported alle…