The main purpose of this study is to assess the effect of food on balcinrenone/ dapagliflozin pharmacokinetics in fed and fasted state and pharmacokinetics of balcinrenone when dosed with a P-gp inhibitor in healthy participants.
Age range
18 Years – 55 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Area under concentration-time curve from time zero to infinity (AUCinf)
Timeframe: From Day 1 to Day 10
Area under concentration-curve from time 0 to the last quantifiable concentration (AUClast)
Timeframe: From Day 1 to Day 10
Maximum observed drug concentration (Cmax)
Timeframe: From Day 1 to Day 10
Terminal elimination half-life (t1/2λz)
Timeframe: From Day 1 to Day 10
Time to reach maximum observed concentration (tmax)
Timeframe: From Day 1 to Day 10
Apparent volume of distribution based on the terminal phase (Vz/F)
Timeframe: From Day 1 to Day 10
Apparent total body clearance (CL/F)
Timeframe: From Day 1 to Day 10
Renal Clearance (CLR) (balcinrenone only)
Timeframe: From Day 1 to Day 10
Drug concentration in plasma at 24 hours post-dose (C24)
Timeframe: From Day 1 to Day 10