The purpose of this study is to measure the effect of multiple doses of AZD2389 on the pharmacokinetics (PK) of midazolam, caffeine, and bupropion in healthy participants.
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Ratio of treatment to reference based on Cmax (RCmax)
Timeframe: Period 1: Days 1-4; Period 2: Days 5-13; Period 3: Days 14-18.
Ratio of treatment to reference based on AUCinf (RAUCinf)
Timeframe: Period 1: Days 1-4; Period 2: Days 5-13; Period 3: Days 14-18.
Ratio of treatment to reference based on AUClast (RAUClast)
Timeframe: Period 1: Days 1-4; Period 2: Days 5-13; Period 3: Days 14-18.
Ratio of area under concentration-curve from time 0 to 24 hours post-dose (AUC0-24)
Timeframe: Period 1: Days 1-3; Period 3: Days 15-18.