Detection of Bleeding Disorders Diagnosed After Vaginal Delivery Complicated by Severe Postpartum… (NCT06970860) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Detection of Bleeding Disorders Diagnosed After Vaginal Delivery Complicated by Severe Postpartum Hemorrhage
France150 participantsStarted 2025-11-15
Plain-language summary
A cohort study designed to detect bleeding disorders diagnosed in women who experienced severe postpartum hemorrhage after vaginal delivery
Who can participate
Age range18 Years
SexFEMALE
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Inclusion Criteria:
* Women ≥ 18 years old
* Who experienced severe postpartum hemorrhage, defined as blood loss ≥ 1000 mL, following a vaginal delivery in the previous 12 months, in a maternity unit in Finistère
Exclusion Criteria:
* Women who are pregnant at the time of inclusion
* Women with a known hereditary bleeding disorder (Willebrand's disease, hemophilia carrier, etc.) or acute or chronic Immune thrombocytopenia (ITP) prior to delivery.
* Women with a known other bleeding pathology prior to delivery
* Women taking a treatment that interferes with hemostasis, such as aspirin, anticoagulants or non-steroidal anti-inflammatory drugs (biological sampling may be postponed until after the interfering treatment has stopped, in the case of occasional use of the latter).
* Women on long-term anticoagulant or antiaggregant therapy
* Women under legal protection,
* Women not affiliated to the French social security system.
What they're measuring
1
Rate of biological test results suggestive of a bleeding disorder, correlated with the clinical bleeding phenotype, within the cohort