FMRF Combined With 30% SSA in the Treatment of Rosacea (NCT06969300) | Clinical Trial Compass
CompletedNot Applicable
FMRF Combined With 30% SSA in the Treatment of Rosacea
China15 participantsStarted 2023-12-01
Plain-language summary
This study was a single-center, case-by-case, bilateral facial comparison study. A total of 15 patients were included. On the day of enrollment, after the completion of the test items, treatment was carried out (full face gold micro-needling + 30% salicylic acid on the half face), and on-site follow-up was conducted 1 week later, 2 weeks later follow-up was conducted and the second acid brushing treatment was performed, 4 weeks later follow-up was conducted and the third acid brushing treatment was performed, on-site follow-up was conducted at the 8th week and the 12th week, and the follow-up contents included: Visia photography, camera photography, non-invasive skin testing, questionnaire assessment, etc. The study duration was 12 weeks.
Who can participate
Age range18 Years – 60 Years
SexALL
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Inclusion criteria
✓. According to the latest diagnostic criteria of the American Rosacea Society (2017 version) - Annex 1, patients diagnosed with the main phenotype of erythema and telangiectasia.
✓. The therapeutic response to the medication is unsatisfactory and the condition is prone to relapse.
✓. Age range: 18 to 60 years old
✓. The patient voluntarily participated in this clinical study and signed the written informed consent form.
Exclusion criteria
✕. The patient has other skin disorders on the face, such as melasma, freckles and seborrheic dermatitis, which may affect the judgment of the test results.
✕. Individuals who are allergic to the test drug or have hypersensitive constitution.
✕. Patients who are pregnant, about to become pregnant or are lactating.
✕. Patients with acne during the consultation.
✕. Patients who had undergone facial injections or surgeries within the past two months before the trial.
What they're measuring
1
The range, quantity and degree of facial erythema
Timeframe: Before the first treatment, 1 week, 2 weeks, 4 weeks, 8 weeks, 12 weeks
2
Erythema score
Timeframe: Before the first treatment, 1 week, 2 weeks, 4 weeks, 8 weeks, 12 weeks
3
TEWL
Timeframe: Before the first treatment, 1 week, 2 weeks, 4 weeks, 8 weeks, 12 weeks
4
MI
Timeframe: Before the first treatment, 1 week, 2 weeks, 4 weeks, 8 weeks, 12 weeks
5
L*a*b
Timeframe: Before the first treatment, 1 week, 2 weeks, 4 weeks, 8 weeks, 12 weeks
6
The moisture content of the stratum corneum
Timeframe: Before the first treatment, 1 week, 2 weeks, 4 weeks, 8 weeks, 12 weeks
7
Skin elasticity
Timeframe: Before the first treatment, 1 week, 2 weeks, 4 weeks, 8 weeks, 12 weeks
Trial details
NCT IDNCT06969300
SponsorSecond Affiliated Hospital of Xi'an Jiaotong University