The purpose of this trial is to evaluate the safety and immunogenicity of CVM150 and CVM26. The trial will enroll up to 60 healthy participants.
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The percentage of participants who experience any solicited local reactogenicity symptom pertaining to intranasal administration through 7 days post-vaccination (Day 1 through Day 8)
Timeframe: Day 1 through Day 8
The percentage of participants who experience any solicited systemic reactogenicity symptom through 7 days postvaccination (Day 1 through Day 8)
Timeframe: Day 1 through Day 8
The percentage of participants who experience any unsolicited adverse event (AE) through 28 days post-vaccination (Day 1 through Day 29)
Timeframe: Day 1 through Day 29
The percentage of participants who experience the following events through 6 months post-vaccination: • SAEs • MAAEs • AESIs • NOCMCs
Timeframe: Day 1 through Day 181
The percentage of participants who experience the following events through 12 months post-vaccination: • SAEs • MAAEs • AESIs • NOCMCs
Timeframe: Day 1 through Day 366