CompletedNot Applicable

Efficacy Of Oral Dexamethasone Versus Parenteral Dexamethasone In The Management Of Mild To Moderate Croup

Pakistan200 participantsStarted 2024-10-01

Plain-language summary

Croup (laryngotracheobronchitis) is a viral infection of the upper airway that causes throat swelling, leading to a barking cough, stridor, and hoarseness. It mainly affects children aged 6 months to 12 years, peaking at around 2 years. Most cases are mild and self-limiting. Emergency treatments include cool mist, nebulized epinephrine, and steroids. Steroid therapy, particularly dexamethasone (oral or intramuscular), is commonly used, with recent studies suggesting intramuscular dexamethasone may be more effective. However, most research has focused on hospitalized patients, and there is a lack of local data for mild cases. This study aims to address that gap and improve patient counseling and future research

Who can participate

Age range2 Years – 12 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient age 2 to 12 years * Both genders * Diagnosed with croup as operational definitions Exclusion Criteria: * Patients with chronic pulmonary disease like tuberculosis, * Allergy or contraindication of corticosteroid (history of tuberous sclerosis, history of varicella infection during the past three weeks), to corticosteroids, * history of corticosteroid administration during the last four weeks, * foreign body * patients with immunodeficiency disorder

What they're measuring

Settlement of symptoms of Croup

Timeframe: within 24 hours

Trial details

NCT IDNCT06959407

SponsorArooj Khan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-03-01

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