Effects of Surgical Correction of Nasal Obstruction on Oxygen Uptake and Ventilation Volume (NCT06957262) | Clinical Trial Compass
CompletedNot Applicable
Effects of Surgical Correction of Nasal Obstruction on Oxygen Uptake and Ventilation Volume
22 participantsStarted 2017-01-01
Plain-language summary
This retrospective study aims to evaluate the effect of surgical correction of nasal obstruction on aerobic performance parameters in male athletes aged 20-32 years. The main questions it aims to answer are:
* Does nasal obstruction surgery impact running economy and ventilation during exercise?
* Does it affect oxygen consumption during submaximal running efforts?
Researchers will retrospectively compare male athletes who underwent nasal obstruction surgery (experimental group) to matched athletes without nasal obstruction (control group) to assess changes in respiratory function and exercise performance.
Participants were assessed by:
* Acoustic rhinometry to measure nasal cavity dimensions.
* The Nasal Obstruction Symptom Evaluation (NOSE) scale and Epworth Sleepiness Scale (ESS) to evaluate nasal obstruction symptoms and daytime sleepiness.
* Incremental treadmill exercise tests to collect data on gas exchange, oxygen consumption, ventilation, and running economy before and after the surgical intervention (or across a similar time period for the control group).
Who can participate
Age range
18 Years – 40 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
For Experimental Group (EG):
* Diagnosed with nasal obstruction due to septal deviation and/or inferior turbinate hypertrophy
* Experiencing nasal breathing difficulties and sleep disturbance
* Deemed eligible for septoplasty and/or inferior turbinoplasty following physical and endoscopic examination
* Voluntarily agreed to participate in the study
* For Control Group (CG):
* No reported nasal obstruction or breathing complications
* Matched with EG participants by age, sport discipline, training level, and VO₂max (with a maximum variation of ±5%)
* Willing to follow a similar training program to their matched EG counterparts between pre- and post-testing periods
Exclusion Criteria:
* History of nasal surgery
* Presence of cardiopulmonary diseases
* Musculoskeletal disorders affecting physical performance or exercise testing
* Inability or unwillingness to follow the pre- and post-test training schedule
* Any surgical complication that would interfere with post-operative participation in physical testing (note: none occurred in this study)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.