Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions (NCT06933290) | Clinical Trial Compass
RecruitingNot Applicable
Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions
United States13 participantsStarted 2025-03-24
Plain-language summary
To determine the effect of flavored, carbonated drinks on salivary flow rate, saliva composition, and taste perceptions compared with control drinks (water, carbonated water, non-carbonated)
Who can participate
Age range18 Years – 45 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Subject is male or female
* If female, subject is not pregnant or nursing (based on self-report)
* Subject is 18-45 years of age, inclusive
* Subject is a regular consumer of carbonated drinks (questionnaire)
* Subject is willing to avoid alcohol consumption 24 hours prior to visits
* Subject is willing to fast (no food or gum) for 2 hours prior to study sessions
* Able to speak, write, and read English
* Provision of written consent to participate
Exclusion Criteria:
* Subject smokes, vapes, or uses any nicotine/tobacco products (or has quit for less than 6 months)
* Subject currently has or recently had an illness (cold, flu, COVID) within the past month
* Subject has a condition affecting the oral cavity such as Xerostomia (dry mouth), Sores/lesions, Untreated dental caries, Major dental implants/appliances (including dentures)
* Subject has a reduced sense of taste (dysgeusia) or smell (parosmia)
* Subject has a health condition that would interfere with the study as indicated on the general health questionnaire (GHQ) (including cardiovascular, renal, or metabolic diseases)
* Subject has participated in a clinical trial within the past 30 days
* Subject has participated in any PepsiCo trial within past 6 months
* Subject has a condition or is taking medication that the investigator believes would interfere with his/her ability to provide informed consent, comply with the study protocol, which might confound the interpretation of the study results,…
What they're measuring
1
Salivary flow rate
Timeframe: At each of six 2 hour test sessions 2-8 days apart at same time of day