RecruitingNot Applicable

A Preventive Behavioral Intervention for Young Adults With Psychotic Experiences

United States192 participantsStarted 2025-02-10

Plain-language summary

This is a randomized controlled trial testing the efficacy of Resilience Training in college students with elevated transdiagnostic risk for developing a serious mental illness.

Who can participate

Age range18 Years – 30 Years

SexALL

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Inclusion criteria

✓. 18-30 years old
✓. Enrolled as a first or second year student (i.e., freshman or sophomore) in an undergraduate program at the college or university where the intervention takes place
✓. Students who endorse some psychotic experiences (Peter's et al. Delusion Inventory (PDI) score \> 3)

Exclusion criteria

✕. Inability to provide informed consent
✕. Not proficient in English
✕. Current self-reported Diagnostic Statistical Manual 5 (DSM-5) diagnosis with active symptoms (such as active psychotic symptoms, current suicidality, serious active alcohol or substance use, marked deterioration in functioning over the prior month) determined by clinical interview with participant, or self-report of a psychiatric diagnosis that necessitates close monitoring or individual therapy and/or inpatient or partial hospitalization
✕. Current enrollment in psychological or behavioral health treatment.
✕. Current use of psychotropic medications (other than stimulants) prescribed by a physician.
✕. A diagnosis of a serious, chronic mental illness as determined by the Mini-International Neuropsychiatric Interview (MINI)

What they're measuring

Peters Delusions Inventory

Timeframe: Baseline, 4-weeks, 6 month, 12 months, and 24 months

Trial details

NCT IDNCT06929442

SponsorMassachusetts General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-12-01

Contact for this trial

Daphne J Holt, MD, PhD

617-726-7618 dholt@mgh.harvard.edu

View on ClinicalTrials.gov More Psychotic Disorders trials