Controlled hypotension is currently used in spinal surgery to reduce bleeding at the surgical site, improve the surgeon's visibility, and decrease intraoperative blood loss. Although controlled hypotension is considered a beneficial method from a surgical perspective, it is important to be cautious about its side effects. One such side effect is cerebral perfusion insufficiency, which can be managed by monitoring cerebral circulation through regional cerebral oxygen saturation (rSO2). The aim of this study is to compare the effects of controlled hypotension at specific MAP ranges on cerebral oxygen saturation.
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Near infrared spectroscopy (NIRS)
Timeframe: 5 minutes before induction of anesthesia
Near infrared spectroscopy (NIRS)
Timeframe: 5 minutes after intubation
Near infrared spectroscopy (NIRS)
Timeframe: 5 minutes after positioning prone
Near infrared spectroscopy (NIRS)
Timeframe: 1 minutes after first surgical incision is made
Near infrared spectroscopy (NIRS)
Timeframe: the time after one minutes target MAP value
Near infrared spectroscopy (NIRS)
Timeframe: the time after ten minutes target MAP value
Near infrared spectroscopy (NIRS)
Timeframe: the time after 20 minutes target MAP value
Near infrared spectroscopy (NIRS)
Timeframe: 5 minutes after extubation
Near infrared spectroscopy (NIRS)
Timeframe: postextubation after 15 minutes