Background: The skin microbiota influence skin health in several skin diseases and atopic dermatitis (AD). Presence of Staphylococcus have been associated to a sever course of the disease. Objectives: The aim of the study is to investigate the influence of bacteria, and the skin microbiota on the inflammation and skin barrier. Moreover, dysbiosis in the microbiota, the inflammation profile, the skin barrier damage will be related to objective and patient oriented measures. Importance: Knowledge of interactions between host defense, skin barrier and bacterial colonizing skin can facilitate development of new prevention and treatment strategies to control microbial impact in skin diseases and eczema.
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Skin microbiota
Timeframe: At baseline/enrollment through study completion, an average of 1 year.
Skin Barrier impairment tewl
Timeframe: At baseline/enrollment through study completion, an average of 1 year.
EASI
Timeframe: At baseline/enrollment through study completion, an average of 1 year.
Patient oriented outcome measures RECAP
Timeframe: At baseline/enrollment through study completion, an average of 1 year.
Patient oriented outcome measures POEM
Timeframe: At baseline/enrollment through study completion, an average of 1 year.
Patient oriented outcome measures DLQI
Timeframe: At baseline/enrollment through study completion, an average of 1 year.
Patient oriented outcome measures NRS Itch
Timeframe: At baseline/enrollment through study completion, an average of 1 year.