Comprehensive Ambulatory Antibiotics for the Treatment of Congenital Syphilis

Inclusion criteria

• ✓. Infants at risk of congenital syphilis at birth defined as:
• ✓. an infant born to a mother who tests positive for syphilis in pregnancy using registered and licensed locally-available diagnostic tests for example but not limited to a Treponemal rapid POCT, an RPR or both.
• ✓. the mother is untreated in the current pregnancy defined as:
• ✓. Infants who are asymptomatic for a diagnosis of congenital syphilis following application of a clinical proforma by the study team (Appendix 1)
• ✓. Infants who are less than \<= 7 days of life AND with a post-menstrual age (PMA) of 34-42 weeks (Appendix 2).
• ✓. Infants who are tolerating enteral feeds, including if they are being administered by an NG tube.