Transcranial Direct Current Stimulation for Post Treatment Lyme Disease

Inclusion Criteria: * History of diagnosis of Lyme disease by a health care provider, meeting criteria for either definite or probable or possible LD * Willingness to provide documentation of prior LD testing and/or related medical records * Total prior antibiotic treatment for LD was at least 2 courses of antibiotic therapy * Have cognitive symptoms attributed to Lyme disease that have persisted or returned despite antibiotic therapy * Current cognitive symptoms interfere with function and/or cause distress * Have evidence of slowed processing speed on a screening measure * Participant is willing to be off of antibiotic treatment for tick-borne disease for at least 4 weeks prior to final determination of study eligibility and for the duration of the 12-week study. * Participant expresses willingness to not start new medications that might affect treatment outcome during the trial (unless medically necessary), and willingness to inform study staff regarding any changes in medication * Live in the US or Canada and comfortable speaking English * Age 18-70 * Stable and continuous access to internet service * Adequate home facilities (enough space, access to quiet and distraction free area) * Able to commit to the 12-week study period (4 weeks of training sessions and an 8-week post treatment visit) * Estimated intellectual ability \>= 85 Exclusion Criteria: \- Medical Illness: Any of the following: a. Unstable non-Lyme-related chronic medical illness over the last 12 months (…