Effect of Open Kinetic CKE Exercises With NES in Patients With Post-ACL Reconstruction Surgery (NCT06913543) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Effect of Open Kinetic CKE Exercises With NES in Patients With Post-ACL Reconstruction Surgery
Pakistan58 participantsStarted 2025-03-20
Plain-language summary
"Anterior cruciate ligament (ACL) reconstruction is a commonly performed surgical procedure for restoring knee stability in patients following ACL injuries. Despite surgical success, postoperative rehabilitation remains crucial for improving functional outcomes, addressing quadriceps strength deficits, and reducing recovery time.
Who can participate
Age range
18 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Both genders aged 18-45 years
* Subjects who have undergone unilateral primary ACL reconstruction surgery
* Subjects who are exactly 4 weeks post-surgery at the start of the study
* Subjects who received a hamstring tendon autograft or patellar tendon graft for ACL reconstruction
* Subjects cleared by a physician to begin open kinetic chain exercises in their rehabilitation program
* Subjects who are generally healthy with no significant comorbidities that could interfere with rehabilitation
* Willingness to provide informed consent and commit to the entire duration of the study
Exclusion Criteria:
* Presence of additional knee injuries (e.g., meniscal tears, collateral ligament injuries) that might affect rehabilitation
* History of prior ACL injury or reconstruction on the same knee
* Patients who underwent reconstruction of other ligaments along with the ACL
* Presence of conditions (e.g., rheumatoid arthritis, osteoarthritis, uncontrolled diabetes) that could influence recovery
* Any significant injury or surgery to the opposite knee within the last six months
* Factors that indicate a high risk of non-compliance with the rehabilitation protocol, such as poor availability, or lack of commitment to follow the exercise regimen
* Conditions affecting neuromuscular control that could interfere with exercise performance or rehabilitation response
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.