This study aims to find out whether an adapted version of an existing cognitive rehabilitation program, CIRCuiTS (https://www.circuitstherapyinfo.com), can be used to improve everyday thinking skills for people with Multiple Sclerosis (MS). People living with MS have worked with the study's researchers to adapt CIRCuiTS to meet their needs. They shared the thinking challenges they experience and suggested changes to the program's content and how it is delivered. This study will test whether this adapted version can be delivered practically to people with MS in a trial setting and explore its potential benefits. The findings will help plan a larger trial testing how effective CIRCuiTS is in helping people with MS. Twenty-four people with MS will take part in this pilot trial. Each person will be randomly assigned to start the program either right away or after a 13-week wait. The therapy program involves up to 36 hours of therapist-led and independent sessions over 12 weeks in which the participant builds thinking skills through developing personal strategies for carrying out digital versions of tasks they find challenging. The practicality of delivering the program to people with MS will be judged based on whether problems arise in the trial, such as not being able to recruit enough people or participants not liking it. To explore its potential benefits, the study will check for improvements in progress toward personal goals, thinking abilities, emotional well-being, chronic tiredness, and daily living skills after the therapy. If delivering CIRCuiTS to people with MS is found to be both practical and acceptable to participants, the findings of this trial will be used to design a larger-scale trial of its effectiveness. Ultimately, the goal of this project is to improve the quality of life of people living with cognitive difficulties related to MS.
Age range
18 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Recruitment rate
Timeframe: Until the end of the study, estimated 15 months
Ethnic enrolment diversity
Timeframe: Until the end of the study, estimated 15 months
Gender enrolment diversity
Timeframe: Until the end of the study, estimated 15 months
Completion rate
Timeframe: Until the end of the study, estimated 15 months
Midpoint retention
Timeframe: Until the end of the study, estimated 15 months
Dropout
Timeframe: Until the end of the study, estimated 15 months
Serious adverse events
Timeframe: Until the end of the study, estimated 15 months
Manageability of adverse events
Timeframe: Until the end of the study, estimated 15 months
Data completeness
Timeframe: Until the end of the study, estimated 15 months
Specific measure completeness
Timeframe: Until the end of the study, estimated 15 months
Operational feasibility
Timeframe: Until the end of the study, estimated 15 months
Adherence: Therapy
Timeframe: Until the end of the study, estimated 15 months
Adherence: Independent sessions
Timeframe: Until the end of the study, estimated 15 months
Specific measure acceptability
Timeframe: Until the end of the study, estimated 15 months
Program acceptability
Timeframe: Until the end of the study, estimated 15 months