RecruitingNot Applicable

Early Intra-aortic Balloon Pump Use After Venoarterial Extracorporeal Membrane Oxygenation

China358 participantsStarted 2026-03-22

Plain-language summary

The goal of this multicenter, randomized trial is to compare early early left ventricular unloading by Intra-aortic Balloon Pump (IABP) versus conventional approach in patients with cardiogenic shock (CS) undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO). The main question it aims to answer is : • If left ventricular unloading by IABP as compared with the conventional approach will improve the outcomes in patients undergoing VA-ECMO.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Age of ≥18
✓. Cardiogenic shock(defined as a systolic blood pressure of less than 90 mm Hg for more than 30 minutes or the initiation of catecholamines to maintain a systolic pressure of more than 90 mm Hg, an arterial lactate level of more than 3 mmol per liter, and signs of impaired organ perfusion)
✓. Successful implantation of VA-ECMO
✓. Informed consent

Exclusion criteria

✕. SCAI shock stage A or B
✕. Presence of moderate to severe aortic insufficiency or aortic dissection
✕. Severe peripheral vascular disease
✕. Post-cardiotomy cardiogenic shock(non-CABG procedure) or bridging to cardiac procedure(heart transplantation or LVAD).
✕. VA-ECMO for definite non-cardiac causes
✕. Isolated right ventricular failure
✕. V-A ECMO usage confined to the period during surgery or other interventions
✕. Ischemic mechanical complications(eg Ventricular septal defect, papillary muscle rupture)

What they're measuring

30-day mortality

Timeframe: 30 days

Trial details

NCT IDNCT06872021

SponsorBeijing Anzhen Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-09-01

Contact for this trial

Xiaotong Hou, MD, PhD

010-64456631 xt.hou@ccmu.edu.cn

View on ClinicalTrials.gov More ECMO trials