Clinical and Radiographic Evaluation of Potassium Nitrate in Polycarboxylate Versus Mineral Triox… (NCT06871709) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Clinical and Radiographic Evaluation of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate in Vital Pulpotomy in Primary Molars
Egypt50 participantsStarted 2025-05-30
Plain-language summary
The purpose of this RCT is to compare the clinical/radiographic outcomes of Potassium nitrate in polycarboxylate cement and MTA as pulpotomy biomaterials used for asymptomatic vital primary lower second molar and this will help to clinically evaluate the use of alternative material in vital pulpotomy in primary molars with deep carious cavities.
Emphasis is set on avoiding total pupectomy and maintaining radicular pulp vitality therefore maintain the tooth in a viable condition till it's shedding and eruption of the permanent successor.
Who can participate
Age range
4 Years – 7 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Children aged 4 to 7 years, in good general health.
. Children with vital, deeply carious primary molars.
. No history of spontaneous pain, pathological mobility, draining sinus tract, redness or swelling of the vestibule.
. Normal gingival and periodontal condition, with no sensitivity to vestibular palpation, and no pain on percussion test.
. No sign of radiolucency in periapical or furcation area.
. No widening of PDL space or loss of lamina dura continuity.
. No evidence of internal/external pathological root resorption.
Exclusion criteria
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Clinical success rate
Timeframe: Baseline, 1 week, 3 month, 6, 9 and 12 months after treatment
Trial details
NCT IDNCT06871709
SponsorCairo University
Sponsor typeOTHER
Study typeINTERVENTIONAL
Primary completion2026-01-01
Contact for this trial
Mariam M El-Mosallamy, bachelor's degree in dentistry