The purpose of this pilot study was to compare two commonly employed intravenous drug combinations; I) nitrous oxide, midazolam, fentanyl, and ketamine and II) the same combination with substitution of propofol for ketamine, for use during wisdom teeth extraction. Measures of recovery, amnesia testing 20 minutes after induction and after completion of recovery tests, patient satisfaction, and surgeon satisfaction will be evaluated. The data from this pilot study will be used to obtain preliminary estimates of effect sizes and to select primary and secondary endpoints for the design of a larger scale and more definitive trial of the two anesthetic approaches.
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Patient Satisfaction
Timeframe: Postoperatively, approximately 1 hour on day of procedure
Surgeon Satisfaction
Timeframe: Postoperatively, approximately 1 hour
Recovery - Paper Test
Timeframe: Change from preoperatively to postoperatively, approximately 2-3 hours total on day of procedure
Recovery - One Leg Standing Test
Timeframe: Change from preoperatively to postoperatively, approximately 2-3 hours total on day of procedure
Amnesia - Visual Stimuli
Timeframe: Intraoperatively and postoperatively, up to 1-2 hours on day of procedure
Amnesia - Tactile Stimuli
Timeframe: Intraoperatively and postoperatively, up to 1-2 hours on day of procedure