CompletedNot Applicable

Evaluation of the Effectiveness of Different Procedures on Palatinal Wound Healing After Free Gingival Graft Surgery.

Turkey (Türkiye)67 participantsStarted 2023-05-15

Plain-language summary

This study aimed to help determine the appropriate method to accelerate wound healing at the free gingival graft donor site and to minimize the patient's postoperative complaints. For this purpose, gelatin sponge impregnated with injectable platelet-rich fibrin (I-PRF), gelatin sponge impregnated with 0.8% polyvinylpyrrolidone sodium hyaluronate (HA) gel, and standard gelatin sponge application were compared to the secondary wound site on the palate. The main questions aimed at being answered are: * Does the use of I-PRF or HA accelerate wound healing in patients? * Does the use of I-PRF or HA reduce pain and burning symptoms? * For this purpose, gelatin sponge impregnated with injectable platelet-rich fibrin (I-PRF), gelatin sponge impregnated with 0.8% polyvinylpyrrolidone sodium hyaluronate (HA) gel, and standard gelatin sponge application were compared to the secondary wound site on the palate. Participants will: * They will record whether there is pain and burning for 7 days after the operation. * They will record if there is bleeding in the palate area. * They will write the number of painkillers they use daily. * They will visit the clinic on the 3rd, 5th, 7th, 14th, 21st, 28th days and 1st and 3rd months after the operation.

Who can participate

Age range

18 Years – 58 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Inclusion criteria for the study were; * patients older than 18 and * systemically healthy patients, * who didn't use drugs that affect wound healing, * didn't have coagulation disorder and nausea, and * were not anti-inflammatory drug allergy sufferers. Exclusion Criteria: * Exclusion criteria for the study were; * patients who had systematic disorders (such as diabetes, hypertension, radiotherapy, chemotherapy), * patients who were former or active smokers and alcohol users, * pregnant and breastfeeding, lactation, menstruation, * patients with poor oral hygiene, and patients who didn't attend regular check-ups.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Landry Wound Healing Index (WHI)

Timeframe: 1st, 3rd, 7th, 14th, 21st, 28th days and 1st and 3rd month after the surgical procedure

Trial details

NCT IDNCT06867055

SponsorSEVAL CEYLAN ŞEN

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-15

View on ClinicalTrials.gov More Insufficient Keratinized Gingiva trials