Researchers have designed a study medicine called opevesostat as a new way to treat prostate cancer. The purpose of this study is to learn what happens to opevesostat in a person's body over time (a pharmacokinetic \[PK\] study). Researchers will compare what happens to opevesostat in the body when it is given to healthy participants and participants with moderate hepatic (liver) impairment.
Age range
18 Years
Sex
MALE
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Area Under the Concentration Versus Time Curve from 0 to Infinity (AUC0-inf) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Area Under the Concentration Versus Time Curve from 0 to the Last Quantifiable Sample (AUC0-last) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Area Under the Concentration Versus Time Curve from 0 to 24 hours (AUC0-24) of Opevesestat
Timeframe: At designated timepoints (up to approximately 24 hours post-dose)
Maximum Observed Concentration (Cmax) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Time to Maximum Concentration (Tmax) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Apparent Terminal Half-life (t1/2) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Apparent Clearance (CL/F) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Apparent Volume of Distribution During Terminal Phase (Vz/F) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)