Researchers have designed a study medicine called opevesostat as a new way to treat prostate cancer. The purpose of this study is to learn what happens to opevesostat in a person's body over time (a pharmacokinetic \[PK\] study). Researchers will compare what happens to opevesostat in the body when it is given to healthy participants and participants with moderate hepatic (liver) impairment.
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Area Under the Concentration Versus Time Curve from 0 to Infinity (AUC0-inf) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Area Under the Concentration Versus Time Curve from 0 to the Last Quantifiable Sample (AUC0-last) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Area Under the Concentration Versus Time Curve from 0 to 24 hours (AUC0-24) of Opevesestat
Timeframe: At designated timepoints (up to approximately 24 hours post-dose)
Maximum Observed Concentration (Cmax) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Time to Maximum Concentration (Tmax) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Apparent Terminal Half-life (t1/2) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Apparent Clearance (CL/F) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)
Apparent Volume of Distribution During Terminal Phase (Vz/F) of Opevesestat
Timeframe: At designated timepoints (up to approximately 96 hours post-dose)