CompletedNot Applicable

Health Impacts of Street Vended Fruits

Bangladesh639 participantsStarted 2025-03-06

Plain-language summary

This study will employ a randomized controlled intervention design to evaluate the health impacts of consuming fresh-cut street-vended fruits, focusing on microbial contamination and gastrointestinal (GI) symptoms. A total of 300 participants will be recruited and divided into treatment (consuming guava, pineapple, or watermelon) and control groups (no fruit consumption). Fruit samples will be analyzed for microbial contamination, including S. aureus and E. coli, using standard microbiological and molecular techniques. Data on GI symptoms will be collected through questionnaires and analyzed using statistical methods, such as Chi-square tests, Kaplan-Meier survival analysis, and Cox proportional hazards regression. Spearman correlation will identify associations between bacterial presence and specific symptoms. Ethical approval will be obtained, and participant safety will be prioritized. Analytical tools, including IBM SPSS, RStudio, and PyCharm, will be utilized for the analyses.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Individuals aged 18-60 years. * Residents of Mymensingh District, Bangladesh. * Willing to consume fresh-cut street-vended fruits (guava, pineapple, or watermelon) for five consecutive days. * Individuals with a self-reported history of gastric acidity issues (for the gastric acidity arms). * Individuals with no history of gastric acidity (for the non-gastric acidity arms). * Participants who have not taken antibiotics, proton pump inhibitors (PPIs), or antacids in the last two weeks. * Willing to provide detailed information on their dietary habits and gastrointestinal symptoms through surveys/questionnaires. * Participants who provide informed consent for participation. Exclusion Criteria: * Individuals under 18 years or over 60 years. * Pregnant or lactating women. * Those with a diagnosed gastrointestinal disorder (e.g., peptic ulcer disease, irritable bowel syndrome, Crohn's disease). * Individuals with a history of chronic infections or immune-compromising conditions (e.g., HIV/AIDS, cancer, diabetes). * Participants who have taken antibiotics, PPIs, or antacids within the last two weeks. * Individuals with known allergies to guava, pineapple, or watermelon. * Those who refuse to consume fresh-cut fruits from street vendors. * Participants who do not provide informed consent or are unable to complete the study period.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Prevalence of Gastrointestinal Symptoms Among Participants After Consumption of Fresh-Cut Fruits

Timeframe: From enrollment to the end of treatment at 10 days

Trial details

NCT IDNCT06858046

SponsorBangladesh Agricultural University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-03-19

View on ClinicalTrials.gov More Gastrointestinal Diseases trials