Clinical Trial of Recombinant Herpes Zoster Vaccine (CHO Cell) in Healthy Chinese Population Aged 40 Years and Older

Inclusion Criteria: * Male or female participants aged 40 years or older at the time of enrollment. * Voluntarily agrees to participate in the trial, fully understands, and signs the informed consent form. * Able to attend all scheduled follow-ups and comply with the clinical trial protocol requirements to complete the trial. * Female participants must meet the following criteria:1)Surgically sterilized or postmenopausal for ≥2 years, or women of childbearing potential (not menopausal or menopausal \<2 years) with a negative pregnancy test and willing to use effective physical contraception (e.g., condoms, intrauterine device) from enrollment until 6 months after full immunization. 2)Agree not to breastfeed from enrollment until 6 months after full immunization. * Axillary temperature ≤37.0°C. Exclusion Criteria: a Exclusion criteria for the first dose: * A history of herpes zoster. * A history of varicella or herpes zoster vaccination. * Close contact with a varicella/herpes zoster patient within the past year. * Received immunoglobulin and/or any blood products within 3 months before vaccination. * Received immunosuppressive treatment within 3 months prior to vaccination (e.g., systemic corticosteroids for ≥14 days, at a dose ≥2 mg/kg/day or ≥20 mg/day of prednisone, or an equivalent dose of prednisone) (excluding inhaled, intra-articular, and topical steroids). * A history of severe allergic reactions to any vaccine or medication (e.g., anaphylactic shock, allergic lar…