CompletedNot Applicable

Intra-Abdominal Sepsis and Relationship Between Cumulative Fluid Balance and Serum Sodium and Chloride Levels and In-Hospital Mortality

Serbia100 participantsStarted 2022-06-01

Plain-language summary

Intra-abdominal sepsis and septic shock in critically ill surgical patients have a high mortality rate. Fluid therapy is one of the initial resuscitation measures, but it can contribute to poor treatment outcomes through fluid overload and accumulation of sodium and chloride. This study aimed to examine an association among cumulative fluid balance and serum sodium and chloride levels in the intensive care unit (ICU) and in-hospital mortality in critically ill surgical patients with intra-abdominal sepsis after emergency surgical treatment. The study was designed as a retrospective, cohort study.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * critically ill surgical patients with intra-abdominal sepsis/septic shock consecutively admitted to a university medical center * Patients who were immediately subjected to surgical treatment for intra-abdominal sepsis/sepstic shock upon hospital admission and postoperative care continued in the ICU for at least seven days Exclusion Criteria: * Patients who were hospitalized in the ICU for less than seven days * immunocompromised * patients with intra-abdominal sepsis as a result of previous abdominal surgery were not included in the study

What they're measuring

Association among cumulative fluid balance and serum sodium and chloride levels in the intensive care unit (ICU) and in-hospital mortality in critically ill surgical patients with intra-abdominal sepsis after emergency surgical treatment.

Timeframe: 2 years

Trial details

NCT IDNCT06838585

SponsorClinical Center of Vojvodina

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-09-01