Adding Amantadine to Pregabalin on Occurrence of Post-thoracotomy Pain Syndrome (NCT06833203) | Clinical Trial Compass
CompletedNot Applicable
Adding Amantadine to Pregabalin on Occurrence of Post-thoracotomy Pain Syndrome
Egypt60 participantsStarted 2023-12-01
Plain-language summary
This study aims to evaluate the additive effect of Amantadine to Pregabaline in the development of post-thoracotomy pain syndrome.
Who can participate
Age range18 Years – 65 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age (18-65) years.
* Both sexes.
* American Society of Anesthesiologists (ASA) Physical status II, III.
* Body mass index (BMI): (20-40) kg/m2.
* Cancer patients undergoing posterolateral thoracotomy incision for cancer lung, mesothelioma or other lung resection procedures.
Exclusion Criteria:
* Patients with known sensitivity or contraindication to drug used in the study.
* History of psychological disorders and/or chronic pain and drug abuse patients.
* Previous administration of antidepressants, anticonvulsants, or opioids before surgery.
* Patient refusal.
* Severe respiratory or cardiac disorders.
* Advanced liver or kidney disease.
What they're measuring
1
Incidence of occurrence of post-thoracotomy pain syndrome