LC-Plasma for Preventing URTIs and Reducing Symptoms (NCT06827327) | Clinical Trial Compass
CompletedPhase 3
LC-Plasma for Preventing URTIs and Reducing Symptoms
Australia637 participantsStarted 2025-03-28
Plain-language summary
The goal of this study is to evaluate the efficacy of the LC-Plasma in preventing upper respiratory tract infections (URTIs) in healthy volunteers. Researchers will compare LC-Plasma to placebo to see if LC-Plasma prevents URTIs. Participants will take a tablet containing LC-Plasma or placebo daily for 24 weeks.
Who can participate
Age range18 Years – 60 Years
SexALL
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Inclusion Criteria:
* Adults aged 18-60 years living in Australia
* Individuals with a history of recurrent upper respiratory tract infections
* Able to provide informed consent
* Generally healthy
* Agree to not participate in another clinical trial while enrolled in this trial
* Agree to maintain their usual daily activities without significant changes. This includes not changing their current diet or stopping/starting a new exercise regimen during entire study period
* Agree not to travel internationally for over 1 month in a single trip during the intervention period (baseline to study completion).
* Females of childbearing potential must a prescribed form of birth control
Exclusion Criteria:
* Serious illness e.g., liver disease, kidney disease, heart disease, mood disorders, neurological disorders such as multiple sclerosis.
* Unstable illness e.g., changing medication/treatment.
* BMI \<18.5, \>30
* Current malignancy (excluding Basal Cell Carcinoma) or chemotherapy or radiotherapy treatment for malignancy within the previous 2 years.
* Individuals with chronic respiratory conditions (e.g., asthma, chronic obstructive pulmonary disease).
* Has current symptoms of an acute sickness.
* Active smokers, nicotine use or drug (prescription or illegal substances) abuse
* Current alcohol use (\>14 alcoholic drinks week)
* Allergic to any of the ingredients in the active or placebo formula
* Pregnant or lactating woman
* People medically prescribed medications within the las…