CompletedPhase 4

Measuring Lactation Initiation After Early Postpartum Injectable Progestin (DMPA) Use Among Women in Dhanusha District of Nepal: A Pilot Study

Nepal40 participantsStarted 2025-03-26

Plain-language summary

This is a pilot study of early postpartum initiation of the injectable progestin contraception, depo medroxyprogesterone acetate (DMPA), among 40 postpartum people. The study aims to assess the feasibility to conduct a larger trial evaluating the effects of early postpartum initiation DMPA on lactation and infant growth outcomes in Nepal.

Who can participate

Age range18 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Currently live in Nepal * Had a vaginal or cesarean delivery of a singleton full-term infant within the past 48 hours * Not yet undergone lactogenesis * Desire to use DMPA as a method of postpartum contraception Exclusion Criteria: * Desire a repeat pregnancy in less than 6 months * Do not intend to exclusively feed infant own human milk for 6 months * Do not have access to a telephone * Any medical contraindication to DMPA * Any contraindication to human milk feeding for their infant * History of breast surgery (augmentation or reduction) * Infant with a major congenital anomaly (will be excluded due to unique challenges with feeding in these populations)

What they're measuring

Enrollment feasibility

Timeframe: 12 weeks

Trial details

NCT IDNCT06816901

SponsorUniversity of California, San Diego

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-07-31

View on ClinicalTrials.gov More Postpartum Contraception trials