Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Ex… (NCT06810271) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Exercise
Canada16 participantsStarted 2025-01-24
Plain-language summary
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS). DOMS is characterized by muscle pain and tenderness that typically resolves within a week. While the precise cause of DOMS is unknown, there is growing evidence implicating damage to the connective tissue that surrounds our muscle fibers and is related to a small amount of inflammation. This inflammation is a normal part of our body's ability to recovery from injuries and may be visualized through the use of ultrasound technology. A variety of recovery techniques have been proposed that may help with the recovery of DOMS such as massage and electrical muscle stimulation, but these are not always accessible. Therefore, we are interested in investigating whether the number of daily steps can affect how you experience DOMS.
Who can participate
Age range
18 Years – 35 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
\- Healthy, recreationally active male and female participants (i.e., weekly MET-minutes \> 3000 assessed by International Physical Activity Questionnaire).
Not having a health condition that would compromise their ability to safely participate in the strenuous physical activity involved in our study screened for by the get active questionnaire.
Between 18 and 35 years old.
Body mass index (BMI) between 18.5-30
Self-reported not having engaged in resistance exercise and/or lower body plyometrics for at least 3 months prior to the study.
Willing to abide by the compliance rules of this study.
Self-reported regular menstrual cycle (25-35d) within the last 3 months (female participants).
Exclusion Criteria:
Inability to adhere to any of the compliance rules judged by the principal investigator or medical doctor.
Self-reported regular tobacco use.
Regular use of non-steroidal anti-inflammatory drugs (e.g., Advil)
Use of oral contraceptives (female participants).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in maximal muscle strength between physical activity levels
Timeframe: Daily assessment (every 24 hours) across 96 hours post-exercise