A Study to Assess the Effect of Ceftobiprole on the PK of Pitavastatin and on Plasma Levels of Coproporphyrin

Main Inclusion Criteria: * Body mass index: 18.0 to 30.0 kg/m2, inclusive * Good physical and mental health * Normal renal function (creatinine clearance ≥ 90 mL/min as determined by the Cockcroft-Gault equation) * Female participants of childbearing potential were required not be pregnant or lactating and had to agree to use adequate contraception * Male subjects, if not surgically sterilized, were required to agree to use adequate contraception * All prescribed medication had to be stopped at least 30 days prior to admission to the clinical research center (an exception was made for hormonal contraceptives) * All over-the-counter medication, vitamin preparations and other food supplements, or herbal medications (e.g., St. John's wort) had to be stopped at least 14 days prior to admission to the clinical research center * Ability and willingness to abstain from alcohol from 48 hours (2 days) prior to Screening and admission to the clinical research center * Ability and willingness to abstain from methylxanthine-containing beverages or food from 48 hours (2 days) prior to admission to the clinical research center Main Exclusion Criteria: * History of relevant drug and/or food allergies, particularly to antibiotics. * Subject received a known potent inhibitor of OATP1B activity within 30 days prior to admission * Subject received a potential inducer of OATP1B activity within 30 days prior to admission * Subject had a history of seizures * Subject had a history of frequent d…