The purpose of this study is to characterize the safety, tolerability, pharmacokinetics, and preliminary efficacy of BMS-986489 in Chinese participants with R/R SCLC (Relapsed/Refractory Small Cell Lung Cancer).
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Number of participants with adverse events (AEs)
Timeframe: Up to 12 months after last participant's first treatment
Number of participants with Serious AEs (SAEs)
Timeframe: Up to 12 months after last participant's first treatment
Number of participants with AEs leading to discontinuation of study treatment
Timeframe: Up to 12 months after last participant's first treatment
Number of participants with select AEs
Timeframe: Up to 12 months after last participant's first treatment
Number of participants with immune-mediated AEs (IMAEs)
Timeframe: Up to 12 months after last participant's first treatment
Number of deaths
Timeframe: Up to 12 months after last participant's first treatment
Number of participants with laboratory abnormalities
Timeframe: Up to 12 months after last participant's first treatment
Maximum observed concentration (Cmax) for BMS-986012
Timeframe: Up to 12 months after last participant's first treatment
Time of maximum observed concentration (Tmax) for BMS-986012
Timeframe: Up to 12 months after last participant's first treatment
Trough observed plasma concentration (Ctrough) for BMS-986012
Timeframe: Up to 12 months after last participant's first treatment
Concentration at the end of a dosing interval (Ctau) for BMS-986012
Timeframe: Up to 12 months after last participant's first treatment
Average concentration over a dosing interval ([AUC(TAU)/TAU]) (Cavg(TAU)) for BMS-986012
Timeframe: Up to 12 months after last participant's first treatment
Area under the concentration-time curve within one dosing interval (AUC(TAU)) for BMS-986012
Timeframe: Up to 12 months after last participant's first treatment
Total body clearance (CLT) for BMS-986012
Timeframe: Up to 12 months after last participant's first treatment
Observed concentration at end of infusion (Ceoi) for BMS-986012
Timeframe: Up to 12 months after last participant's first treatment