The purpose of this study is to characterize the safety, tolerability, pharmacokinetics, and preliminary efficacy of BMS-986489 in Chinese participants with R/R SCLC (Relapsed/Refractory Small Cell Lung Cancer).
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Number of participants with adverse events (AEs)
Timeframe: Up to 19 months after last participant's first treatment
Number of participants with Serious AEs (SAEs)
Timeframe: Up to 19 months after last participant's first treatment
Number of participants with AEs leading to discontinuation of study treatment
Timeframe: Up to 19 months after last participant's first treatment
Number of participants with select AEs
Timeframe: Up to 19 months after last participant's first treatment
Number of participants with immune-mediated AEs (IMAEs)
Timeframe: Up to 19 months after last participant's first treatment
Number of deaths
Timeframe: Up to 19 months after last participant's first treatment
Number of participants with laboratory abnormalities
Timeframe: Up to 19 months after last participant's first treatment
Maximum observed concentration (Cmax) for BMS-986012
Timeframe: Up to 19 months after last participant's first treatment
Time of maximum observed concentration (Tmax) for BMS-986012
Timeframe: Up to 19 months after last participant's first treatment
Trough observed plasma concentration (Ctrough) for BMS-986012
Timeframe: Up to 19 months after last participant's first treatment
Concentration at the end of a dosing interval (Ctau) for BMS-986012
Timeframe: Up to 19 months after last participant's first treatment
Average concentration over a dosing interval ([AUC(TAU)/TAU]) (Cavg(TAU)) for BMS-986012
Timeframe: Up to 19 months after last participant's first treatment
Area under the concentration-time curve within one dosing interval (AUC(TAU)) for BMS-986012
Timeframe: Up to 19 months after last participant's first treatment
Total body clearance (CLT) for BMS-986012
Timeframe: Up to 19 months after last participant's first treatment
Observed concentration at end of infusion (Ceoi) for BMS-986012
Timeframe: Up to 19 months after last participant's first treatment