The goal of this clinical trial is to investigate how iron status and heavy bleeding during the menopausal transition affect women's cognitive function and quality of life. The main questions it aims to answer are: * What is the association between iron status, cognitive function, mood, quality of family relationships, and quality of life in perimenopausal women? * How does iron repletion, via supplementation, affect cognitive function, mood, quality of family relationships, and quality of life in perimenopausal women? The investigators will compare the effect of iron supplements to a placebo (gelatin capsule) to see if iron supplements could improve iron status, cognitive function, mood, quality of family relationships, and quality of life of iron-deficient and/or anemic women undergoing the menopausal transition. Each participant will: * Make 2 visits (about 2 hours each - baseline and endline) to the Clinical Research Center at Purdue * Make a very brief visit at midpoint (about 10 minutes) for a checkup * Take a daily study supplement or placebo for 4 months
Age range
18 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Iron Status Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Iron Status Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Iron Status Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Iron Status Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Iron Status Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Iron Status Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Iron Status Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Iron Status Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Inflammation Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Inflammation Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Cognitive Function Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Cognitive Function Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Cognitive Function Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Cognitive Function Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Cognitive Function Assessment
Timeframe: From enrollment to the end of treatment at 4 months
Quality of Life
Timeframe: From enrollment to the end of treatment at 4 months
Quality of Life
Timeframe: From enrollment to the end of treatment at 4 months
Assessment of Mood
Timeframe: From enrollment to the end of treatment at 4 months
Assessment of Family Relationships
Timeframe: From enrollment to the end of treatment at 4 months