RecruitingNot Applicable

Study of ICG Fluorescence Imaging in Open Fracture and Infection Patients

United States10 participantsStarted 2025-06-10

Plain-language summary

The purpose of this study is to determine whether an indocyanine green (ICG) fluorescence imaging system (cBPI) can be used to provide surgeons with information about bone health or bone blood flow. This will help surgeons better understand the healing potential of bone and relative risk of complication. This is important to help surgeons select the most appropriate treatment for severe traumatic injuries and infections.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients 18 years of age or older. * Open extremity fracture, planning for management with external fixation, internal fixation or joint fusion. * Fracture Related Infection, planning for management with debridement and possible removal of hardware. * Will have all planned fracture care surgeries performed by a participating surgeon or delegate. * Provision of informed consent. Exclusion Criteria: * Inability of patient to provide informed consent * Fracture of the hand. * Iodine allergy. * Burns at the fracture site.

What they're measuring

Number of participants who undergo an unplanned fracture-related reoperation

Timeframe: 12 Months

Number of participants who experience a post-procedure surgical site infection

Timeframe: 12 Months

Trial details

NCT IDNCT06793644

SponsorDartmouth-Hitchcock Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-10

Contact for this trial

Jon Mikael Anderson

603-653-3306 jon.mikael.anderson@hitchcock.org

View on ClinicalTrials.gov More Fractures, Bone trials