Comparison of the Effect of Cyclizine Versus Metoclopramide on Gastric Residual Volume in Patients Undergoing Bariatric Surgery: A Randomized Double-blinded Clinical Trial

Inclusion Criteria * ● Age (18 - 40). * Body mass index (BMI) 40 to 50 kg/m2.4 * American Society of Anaesthesiologist (ASA) - physical status III. * Patients undergoing bariatric surgery. * Non smokers. Exclusion Criteria: * ● Refusal of the patient * Deviation from fasting times * Patients with empty stomach * Body mass index (BMI) less than 40s kg/m2 * American Society of Anesthesiologists (ASA) physical status class IV. * Systemic diseases may cause delayed gastric emptying (eg: myopathies and myasthenia gravis). * Patients with gastrointestinal diseases which impact the gastric emptying such as hiatus hernia, intestinal disease and gastro-oesophageal reflux disease and patients with history of upper gastrointestinal surgeries. * Use of other medications known to affect gastric motility or secretions (Diphenoxylate, Atropine\& Imodium) or secretions. * Allergy to macrolide or metoclopramide. • a considerable proportion of patients with obesity have diabetes and thus, they cannot be excluded from the study. However, we would exclude patients with long standing diabetes (more than 5 years) who are likely to have delayed gastric emptying. Furthermore, this is a randomized controlled trial and the randomization usually overcomes these points and the demographic data would be displayed in the results to clarify whether there is a balance between the two groups or not.